Our Approach

Research & Computation

SHEPHERD CAN HELP MATCH ANY DRUG IN THE WORLD TO THE RARE CANCERS IN WHICH IT POTENTIALLY WILL WORK BEST

SHEPHERD’s development approach starts by gathering in-depth knowledge of each cancer. This means we understand a host of qualitative and quantitative data that other development companies don’t have the time or incentive to collect:

  • Mutational burden
  • Natural history
  • Patient profiles
  • Treatment landscape
  • Optimal cell lines
  • Leading researchers
  • Clinical trial history

More and Different Data

We don’t just have more data — our data is different.

Unlike traditional discovery engines, we aren’t only looking at molecules, drugs, and genetics. We’re also looking at “soft” data like patient outcomes clinical trial landscape, and business data — information that is harder to turn into numbers.

Our Solution: DELVE

DELVE is a computational system that aims to store every piece of information we gather from hundreds of data sources. DELVE and its laboratory engine ADA promise to:

  • Compare experimental data from our lab with outcomes in literature
  • Automate the identification of potentially synergistic drug combinations
  • Track and assess unexpected laboratory outcomes
  • Automate molecular structure research
  • Identify target overlap across rare cancers
  • Assess development outcomes and help us understand the most important factors for each project’s success

High Tech with Heart

Our proprietary assets combine traditional statistical methods and machine learning techniques with the decades of combined experience our scientists bring to their understand of each disease and to the business landscape.

Where computers stop, we keep going. We augment computational methods with traditional handwork: in-depth literature survey, discussion with researchers, and mathematical deconstructions and statistical analyses of existing data sets.

VENTURING WHERE OTHERS CAN’T

DELVE has Two Goals

1.) Create unparalleled insights into rare cancer.

2.)Reduce the costs and time associated with getting projects into the lab – and out to patients.

DELVE allows us to work faster and more efficiently, form better hypotheses, and achieve insights we could never make on our own. The longer we work, the more data we collect, the more powerful DELVE will become.

Our tools – both traditional and computational – empower our scientists and analysts to reach more patients at an accelerated pace … and where we are today is just the beginning.